The BEST Beef Enchilada Casserole is a hearty, cheesy, and comforting dish that brings all the great flavors of classic enchiladas into one easy-to-make meal. It’s packed with seasoned ground beef, layers of tortillas, melty cheese, and a rich enchilada sauce that ties everything together perfectly. The crispy edges and gooey center make it a favorite for weeknight dinners or casual gatherings.
I love making this casserole because it’s such a crowd-pleaser and super simple to prepare. The best part is that you can put it together ahead of time and bake it right before dinner, so no last-minute stress. Plus, I always add a little extra cheese on top because, let’s be honest, it makes it even better! It’s one of those recipes that always fills the house with amazing smells and makes everyone hungry as soon as it’s in the oven.
My favorite way to serve this beef enchilada casserole is with a big dollop of sour cream, some chopped fresh cilantro, and maybe a side of guacamole or a simple green salad. It’s perfect for a cozy night in, and if you have leftovers, they’re just as delicious the next day. This casserole really feels like a comforting hug on a plate—and I can’t get enough of it!
Key Ingredients & Substitutions
Ground Beef: This is the star of the dish, giving it rich flavor and texture. For a lighter option, you can use ground turkey or chicken. If you prefer a vegetarian version, cooked lentils or crumbled tofu work well.
Enchilada Sauce: Using a good canned sauce saves time, but homemade sauce gives the best flavor. If you prefer mild spice, go for a mild enchilada sauce or reduce chili powder.
Tortillas: Corn tortillas give authentic flavor, but flour tortillas add a softer texture. If you’re gluten-free, use corn tortillas that are labeled gluten-free or gluten-free tortilla alternatives.
Cheese: Sharp cheddar melts nicely and has great taste. You can also use a Mexican cheese blend, Monterey Jack, or even mozzarella. For dairy-free, look for plant-based cheese substitutes.
How Do You Layer the Casserole Without it Getting Messy?
Layering is key for a perfect casserole that holds together well:
- Start with a thin beef layer—spread it evenly on the dish bottom so tortillas don’t stick.
- Arrange tortillas flat, tearing if necessary to fit edges and prevent uneven layers.
- Spread beef mixture evenly over tortillas to avoid dry spots.
- Add cheese on each layer for gooey binding and rich flavor.
- Repeat layers gently pressing down for compactness, but don’t mash.
- If sauce seems thick, add a little water or extra sauce to help keep layers moist during baking.
Taking these steps helps you build a sliceable casserole that’s tasty and holds its shape on your plate.
Equipment You’ll Need
- Large skillet – perfect for browning the ground beef and cooking the sauce evenly.
- 9×13-inch baking dish – roomy enough for layering tortillas and beef for a perfect casserole.
- Wooden spoon or spatula – great for stirring the beef mixture without scratching your pan.
- Cheese grater – to shred the cheese fresh for gooey melted layers.
- Mixing bowl – useful if you want to mix seasonings or layer ingredients separately before assembling.
Flavor Variations & Add-Ins
- Swap ground beef for shredded chicken – works well if you prefer milder meat or want to change up the protein.
- Add black beans or corn – they bring extra texture and a little sweetness for more veggie goodness.
- Mix in diced jalapeños – for a spicy kick that livens up the classic flavors.
- Use pepper jack cheese instead of cheddar – adds creaminess with just a touch of heat.
The BEST Beef Enchilada Casserole
Ingredients You’ll Need:
For the Beef Filling:
- 1 lb ground beef
- 1 medium onion, finely chopped
- 2 cloves garlic, minced
- 1 (10 oz) can red enchilada sauce (or homemade enchilada sauce)
- 1 (4 oz) can diced green chilies (optional)
- 1 tsp ground cumin
- 1 tsp chili powder
- 1/2 tsp smoked paprika
- Salt and pepper, to taste
For Assembly:
- 8-10 small corn or flour tortillas
- 2 cups shredded sharp cheddar cheese (or Mexican blend)
For Topping (Optional):
- 1/2 cup chopped fresh cilantro
- 1 medium tomato, diced
- 2 green onions, chopped
- 1/4 cup finely chopped white onion
- Sour cream, for serving
How Much Time Will You Need?
You will need about 15 minutes to prepare the ingredients and assemble the casserole, and around 25 minutes to bake it. Altogether, this delicious beef enchilada casserole takes about 40 minutes from start to finish.
Step-by-Step Instructions:
1. Preheat and Prepare:
Start by preheating your oven to 375°F (190°C). Lightly grease a 9×13-inch baking dish to make sure your casserole doesn’t stick while baking.
2. Cook the Beef Filling:
In a large skillet over medium heat, add the ground beef and the finely chopped onion. Cook them, breaking up the beef as it browns and the onions soften, about 5–7 minutes. Drain any extra fat to keep it from being greasy.
3. Season the Meat:
Add the minced garlic, ground cumin, chili powder, smoked paprika, salt, and pepper to the skillet. Stir everything together and cook for about 1 minute until the spices smell fragrant.
4. Add the Sauce and Chilies:
Pour in the red enchilada sauce and the diced green chilies if you’re using them. Mix well and let it simmer for 5 minutes, allowing the flavors to blend and the sauce to thicken a bit. Then remove the mixture from heat.
5. Assemble the Casserole:
Put a thin layer of the beef mixture on the bottom of your prepared baking dish – this helps to prevent the tortillas from sticking. Cover with 3-4 tortillas, tearing them as needed so they fit snugly.
Spread one-third of the beef mixture evenly over the tortillas, then add a generous layer of shredded cheese. Repeat the layering with tortillas, beef, and cheese two more times, finishing with cheese on top.
6. Bake:
Place the casserole in the preheated oven and bake for 20 to 25 minutes, until the cheese is melted, bubbly, and golden around the edges.
7. Serve and Garnish:
Let the casserole rest for about 5 minutes after baking. This makes it easier to slice and serve. Top with diced tomatoes, chopped green onions, white onions, and fresh cilantro for a burst of fresh flavor. Serve it with sour cream if you like.
Enjoy your hearty, cheesy beef enchilada casserole — a perfect meal for family dinners or any occasion!
Can I Use Frozen Ground Beef?
Yes! Just make sure to thaw it completely before cooking. Thaw in the fridge overnight or use the defrost setting on your microwave. Cook it right after thawing for best results.
Can I Make This Casserole Ahead of Time?
Absolutely! Assemble the casserole and cover it tightly with foil. Store it in the fridge for up to 24 hours before baking. When ready, bake as directed, adding a few extra minutes if baking from cold.
What Can I Substitute for Corn Tortillas?
Flour tortillas work great and will make the casserole a bit softer. For gluten-free options, use certified gluten-free corn tortillas or even gluten-free wraps.
How Should I Store Leftovers?
Keep leftovers in an airtight container in the fridge for up to 3 days. Reheat gently in the oven or microwave until warmed through, adding a little water or sauce if it feels dry.
